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Pervez Musharraf dies: What is amyloidosis? Symptoms, diagnosis, treatment | World News

Former Pakistan president Pervez Musharraf handed away on Sunday on the age of 79 on the American Hospital in Dubai. He was ailing from amyloidosis and had been present process therapy since March 2016.

Amyloidosis is a uncommon illness, which impacts connective tissues and organs. It results in an irregular deposition of some types of proteins in tissues resulting in organ failure, Dr Prashant Mehta, senior marketing consultant – Medical Oncology/Hematology & Unit Head- BMT, had earlier told HT.

Learn right here: Pervez Musharraf, former Pakistani president, dies at 79: Reports

Signs of amyloidosis

Sufferers ailing from this illness have signs like weight reduction, simple fatigability, waxy pores and skin, pores and skin bruising, enlargement of tongue and deltoids, liver enlargement, coronary heart failure, lack of extreme proteins in urine (nephrotic syndrome), carpal tunnel syndrome and issues of the nerves.

Analysis of amyloidosis

Amyloidosis is mostly recognized in older individuals. The abnormally deposited proteins have a attribute look underneath the microscope which might diagnose the situation. Dr Mehta mentioned an belly fats pad biopsy is mostly used to diagnose the illness however typically it may be initially recognized on a liver biopsy or perhaps a bone marrow or liver biopsy.

Learn right here: Pervez Musharraf’s Delhi connection: His ancestral house in Daryaganj

Types of amyloidosis

Amyloidosis has primarily three varieties. The most typical kind is mostly the AA kind which is attributable to inflammatory ailments like tuberculosis, rheumatoid arthritis and inflammatory bowel issues. The second kind, TTR is troublesome to deal with however newer advances. For extreme organ involvement, organ transplantation is finished. The third kind is the AL or mild chain Amyloidosis which is part of the spectrum of plasma cell dyscrasias and is handled with Immunomodulatory therapy, chemotherapy and steroids, Dr Mehta defined.

Born in a middle-class household of Urdu-speaking Mohajir mother and father in Delhi, Musharraf migrated to Pakistan after the Partition in 1947. He spent his ultimate years in self-exile within the UAE.

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